Paul Sharp, a professor at the University of King’s College London, said in a online scientific journal, [Scientific Reports], "the drug that used for the treatment of Alzheimer's also regenerated stem cells of the tooth helping the damaged part of the tooth cavity grow again"
While testing Tideglusib(the medicine used for the treatment of Alzheimer's) by injecting drugs into experimental rats, the research team found, a surprising side effect, the regeneration of the tooth which changed the direction of their research.
Tideglusib can stimulate stem cells in the pulp of the tooth core thereby stimulating the odontoblast process and strengthening the healing power of dentine, making the teeth regenerate.
Teeth are composed of hard enamel on outside and dentine occupying most of teeth therein, far beneath are blood vessels, nerves and stem cells in the pulp.
Research teams fill wet sponges with Tideglusib in the empty space of the tooth. The tooth is regenerated within about six weeks, and the little sponge melts away by itself because it is made by collagen.
Dr. Nigel Carter, CEO of the Oral Health Foundation said “This is an extremely interesting and novel approach which shows great promise and we look forward to it being translated into a clinical application that could undoubtedly be a progressive step in the treatment of dental disease.
Professor, Paul Sharp said “In addition, using a drug that has already been tested in clinical trials for Alzheimer’s diease provides a real opportunity to get this dental treatment quickly into clinics” and it will be use commonly within three years.
April, 8th, 2017, By Hwa Na Kyung
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